E-cadherin polymorphism ?160 C/A and prostate cancer
نویسندگان
چکیده
منابع مشابه
IGF1 CA-Repeat Polymorphism and Prostate Cancer Development in Isfahan Province of Iran
Background:Prostate cancer is increasing among Iranian men and gene polymorphisms may play a role in the development of prostate cancer. Insulin-like growth factor 1 (IGF1) gene polymorphisms have been deeply explored in different malignancies. In this study, we aimed to explore the association of IGF1 CA repeat length polymorphism with the risk of prostate cancer development i...
متن کاملA single nucleotide polymorphism in the E-cadherin gene promoter-160 is not associated with risk of Korean gastric cancer.
Recently, the -160 C/A polymorphism, located within the regulatory region of Ecadherin promoter, has been shown to influence E-cadherin transcription by altering transcription factor binding. We examined the effect of this polymorphism on risk of gastric cancer and on histological classification of intestinal- and diffuse-type gastric cancer in 146 normal healthy individuals and 292 Korean gast...
متن کاملE-cadherin-160 C/A genotypes and cervical intraepithelial neoplasia.
PURPOSE E-cadherin is a transmembrane glycoprotein with important roles in the maintenance of cervical squamous epithelium integrity. The purpose of this study was to investigate the relationship between E-cadherin-160 C/A polymorphism and cervical intraepithelial neoplasia (CIN). METHODS A case-control study was performed enrolling 70 CIN cases and 107 age-matched healthy controls. Each pati...
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In our recent cancer registry-based study, the incidence of gastric carcinoma was increased up to 5-fold in male relatives of early-onset prostate cancer (PCA) patients. This association may reflect the influence of genetic factors predisposing individuals to both tumor types. Germ-line mutations of the CDH1 gene at 16q have recently been associated with familial gastric cancer. Furthermore, tw...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2004
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.11705